5-Methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile

• CAT Number: R057520
• CAS Number: 138564-59-7
• Molecular Formula: C12H9N3O2S
• Molecular Weight: 259.283
• Purity: ≥95%
• Synonyms: 5-Methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile; 2-(2-Nitroanilino)-5-methylthiophene-3-carbonitrile; Olanzapine Impurity A (EP); USP Olaznzapine Related Compound A
• Storage: -20°C
• IUPAC Name: 5-methyl-2-(2-nitroanilino)thiophene-3-carbonitrile
• InChI: InChI=1S/C12H9N3O2S/c1-8-6-9(7-13)12(18-8)14-10-4-2-3-5-11(10)15(16)17/h2-6,14H,1H3
• InChIKey: NPXUFPFFHANGDL-UHFFFAOYSA-N
• SMILES: CC1=CC(=C(S1)NC2=CC=CC=C2[N+](=O)[O-])C#N

5-Methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile (CAS 138564-59-7) ) is an impurity of Olanzapine. Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication  to treat depression.

Reference

1.Anon., et al.: Fed. Regist., 65, 83041 (2000)
2.Yu, L., et al.: J. Phys. Chem., 106, 544 (2002)