For research use only. Not for therapeutic Use.
5-Methyl Uridine（Cat No.:R003121）is a modified nucleoside commonly found in RNA, where it plays a key role in stabilizing RNA structures and modulating biological processes. The methyl group attached to the uridine base enhances the molecule’s hydrophobic interactions, influencing RNA folding and stability. This modification is crucial in tRNA function and is involved in the regulation of gene expression. 5-Methyl Uridine is widely used in biochemical research, especially in studies focused on RNA modifications, epitranscriptomics, and RNA-based therapeutics. Its availability aids advancements in RNA-related studies.
| Catalog Number | R003121 |
| CAS Number | 1463-10-1 |
| Synonyms | 1-β-D-Ribofuranosylthymine; 5-Methyl-1-β-D-ribofuranosyl-2,4(1H,3H)-?pyrimidinedione; Ribothymidine; Thymine Riboside; β-D-Ribofuranoside Τhymine-1; |
| Molecular Formula | C10H14N2O6 |
| Purity | ≥95% |
| Target | Endogenous Metabolite |
| Storage | Store at -20°C |
| IUPAC Name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione |
| InChI | InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1 |
| InChIKey | DWRXFEITVBNRMK-JXOAFFINSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O |
| Reference | <span style=”color:#000000;”><span style=”font-size:12px;”><span style=”font-family:arial,helvetica,sans-serif;”>1.TEZUKA, MASAKATSU, et al. "Enhancement of antitumor activity of 5-fluorouracil by ribothymidine." <i style=”font-family: Arial, sans-serif; font-size: 13px;”>Journal of pharmacobio-dynamics</i> 9.8 (1986): 683-687.<br /> |
