For research use only, not for therapeutic use.
5′-O-(4,4′-Dimethoxytrityl)-2′-fluoro-D-uridine(Cat No.:M092601), is a modified nucleoside used in nucleic acid synthesis and research. It features a 2′-fluoro modification on the D-uridine base and a 4,4′-dimethoxytrityl protecting group on the 5′ hydroxyl group. This compound is employed in the chemical synthesis of nucleic acids, including modified RNA and DNA molecules. The 4,4′-dimethoxytrityl group protects the 5′ hydroxyl during solid-phase synthesis. 5′-O-(4,4′-Dimethoxytrityl)-2′-fluoro-D-uridine plays a crucial role in molecular biology research, enabling the creation of modified nucleic acids for various applications in genetic studies and gene expression analysis.
Catalog Number | M092601 |
CAS Number | 146954-74-7 |
Molecular Formula | C30H29FN2O7 |
Purity | ≥95% |
Storage | 2-8°C |
IUPAC Name | 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione |
InChI | InChI=1S/C30H29FN2O7/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-27(35)26(31)28(40-24)33-17-16-25(34)32-29(33)36/h3-17,24,26-28,35H,18H2,1-2H3,(H,32,34,36)/t24-,26-,27-,28-/m1/s1 |
InChIKey | CSSFZSSZXOCCJB-YULOIDQLSA-N |
SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)F)O |