5/'-O-(4,4-Dimethoxytrityl)-2/'-O-methyl-N-isobutyrylguanosine-3/'-(2-cyanoethyl-N,N-diisopropyl)pho

• CAT Number: M101952
• CAS Number: 150780-67-9
• Molecular Formula: C45H56N7O9P
• Molecular Weight: 869.94
• Purity: ≥95%
• Target: DNA/RNA Synthesis
• Storage: 2-8°C
• IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
• InChI: InChI=1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1
• InChIKey: IRRDHRZUOZNWDJ-MLLDKZSOSA-N
• SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OC

5′-O-(4,4-Dimethoxytrityl)-2′-O-methyl-N-isobutyrylguanosine-3′-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite（Cat No.:M101952）is a modified guanosine derivative used in oligonucleotide synthesis. The dimethoxytrityl (DMT) group protects the 5’-hydroxyl, while the 2’-O-methyl modification enhances stability against nucleases. The isobutyryl group protects the guanine base during synthesis. This compound is key in constructing RNA and DNA oligonucleotides for research, diagnostics, and therapeutic applications. The cyanoethyl phosphoramidite functionality enables efficient coupling during automated oligonucleotide synthesis, making it crucial for the production of high-fidelity nucleic acids with enhanced stability and modified properties.