For research use only. Not for therapeutic Use.
5-O-demethyl-28-hydroxy-avermectin A1a(CAT: C000466) is a specialized derivative of avermectin A1a, a macrocyclic lactone compound. Avermectins are well-known for their potent anthelmintic (anti-parasitic) properties and are widely used in veterinary and agricultural applications to control and treat parasitic infections in livestock and crops. This specific derivative may have modified pharmacological properties or reduced toxicity compared to the parent compound, making it of interest in drug development or research for potential improvements in parasitic disease control.
| Catalog Number | C000466 |
| CAS Number | 96722-46-2 |
| Synonyms | Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-; 3,2′-[2H]pyran], avermectin A1a deriv.; 28-Hydroxyavermectin B1a; 8alpha-hydroxy-avermectin B1a |
| Molecular Formula | C₄₈H₇₂O₁₅ |
| Purity | ≥95% |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | White to Off-White Solid |
| Storage | 4°C, Hygroscopic |
| Reference | Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178 |
