5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine

For research use only. Not for therapeutic Use.

  • CAT Number: M021192
  • CAS Number: 114745-26-5
  • Molecular Formula: C36H39N5O8
  • Molecular Weight: 669.73
  • Purity: ≥95%
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5′-O-DMT-N2-Isobutyryl-2′-O-methyl-D-guanosine(Cat No.:M021192) is a chemical compound used in nucleic acid synthesis and research. Its mode of action involves serving as a modified nucleoside, containing a 2′-O-methyl group and an isobutyl group at the N2 position of the guanosine base. This modification can be incorporated into RNA or DNA strands during synthesis. Researchers use 5′-O-DMT-N2-Isobutyryl-2′-O-methyl-D-guanosine as a building block in solid-phase synthesis and in the preparation of modified oligonucleotides for various applications. Its unique chemical structure and reactivity make it valuable in the development of nucleic acid-based therapeutics and in studies related to gene expression and regulation.


Catalog Number M021192
CAS Number 114745-26-5
Molecular Formula C36H39N5O8
Purity ≥95%
Storage Store at -20C
IUPAC Name N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI InChI=1S/C36H39N5O8/c1-21(2)32(43)39-35-38-31-28(33(44)40-35)37-20-41(31)34-30(47-5)29(42)27(49-34)19-48-36(22-9-7-6-8-10-22,23-11-15-25(45-3)16-12-23)24-13-17-26(46-4)18-14-24/h6-18,20-21,27,29-30,34,42H,19H2,1-5H3,(H2,38,39,40,43,44)/t27-,29-,30-,34-/m1/s1
InChIKey ISQLJOGRNUQHJX-WIFIACMTSA-N
SMILES CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OC

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