5-O-(E)-p-Coumaroylquinic acid

• CAT Number: I041264
• CAS Number: 5746-55-4
• Molecular Formula: C16H18O8
• Molecular Weight: 338.31
• Purity: ≥95%
• Synonyms: (1S,3R,4R,5R)-1,3,4-trihydroxy-5-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxycyclohexane-1-carboxylic acid
• InChI: InChI=1S/C16H18O8/c17-10-4-1-9(2-5-10)3-6-13(19)24-12-8-16(23,15(21)22)7-11(18)14(12)20/h1-6,11-12,14,17-18,20,23H,7-8H2,(H,21,22)/b6-3+/t11-,12-,14-,16+/m1/s1
• InChIKey: BMRSEYFENKXDIS-OTCYKTEZSA-N
• SMILES: C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC=C(C=C2)O)O)O

5-O-(E)-p-Coumaroylquinic acid, a quinic acid derivative, is a potent phytochemical agent against hepatitis B virus[1].
5-O-(E)-p-Coumaroylquinic acid (compound 12) reduces HBV DNA level in the release of mature HBV particles from HepG2.2.15 cultivation[1].

Reference

[1]. Kim KH, et, al. Isolation of quinic acid derivatives and flavonoids from the aerial parts of Lactuca indica L. and their hepatoprotective activity in vitro. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6739-43.
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