5-O-Feruloylquinic acid

• CAT Number: R047299
• CAS Number: 40242-06-6
• PubChem Substance ID: 10133609
• Molecular Formula: C17H20O9
• Molecular Weight: 368.3
• Purity: 98%
• Target: Tyrosinase
• Appearance: Powder
• IUPAC Name: (1R,3R,4S,5R)-1,3,4-trihydroxy-5-[3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]oxycyclohexane-1-carboxylic acid
• InChI: InChI=1S/C17H20O9/c1-25-12-6-9(2-4-10(12)18)3-5-14(20)26-13-8-17(24,16(22)23)7-11(19)15(13)21/h2-6,11,13,15,18-19,21,24H,7-8H2,1H3,(H,22,23)/b5-3+/t11-,13-,15+,17-/m1/s1
• InChIKey: RAGZUCNPTLULOL-KQJPBSFVSA-N
• SMILES: COC1=C(C=CC(=C1)C=CC(=O)OC2CC(CC(C2O)O)(C(=O)O)O)O

5-O-Feruloylquinic acid (CAS 40242-06-6) is a derivative of quinic acid and a constituent of coffee beans. Studies showed that coffee polyphenols is able to suppress fat accumulation by downregulating SREBP-1c in mice.

Reference

1.Felberg, Ilana, et al. "Effect of simultaneous consumption of soymilk and coffee on the urinary excretion of isoflavones, chlorogenic acids and metabolites in healthy adults." journal of functional foods 19 (2015): 688-699.
2.Ky, C-L., et al. "Caffeine, trigonelline, chlorogenic acids and sucrose diversity in wild Coffea arabica L. and C. canephora P. accessions." Food chemistry 75.2 (2001): 223-230.
3.Murase, Takatoshi, et al. "Coffee polyphenols suppress diet-induced body fat accumulation by downregulating SREBP-1c and related molecules in C57BL/6J mice." American Journal of Physiology-Endocrinology and Metabolism 300.1 (2011): E122-E133.