5/'-O-[(N,N-DIISOPROPYLAMINO)-(2-CYANOETHOXY)PHOSPHINYL]-3/'-O-(4,4/'-DIMETHOXYTRITYL)-THYMIDINE

  • CAT Number: M114796
  • CAS Number: 134031-86-0
  • Molecular Formula: C40H49N4O9P
  • Molecular Weight: 760.81
  • Purity: ≥95%
Inquiry Now

5′-O-[(N,N-Diisopropylamino)-(2-Cyanoethoxy)phosphinyl]-3′-O-(4,4′-Dimethoxytrityl)-Thymidine(Cat No.:M114796)is a synthetic nucleotide derivative commonly used in oligonucleotide synthesis. The compound features protective groups, such as the 4,4′-dimethoxytrityl (DMT) on the 3′-hydroxyl and a cyanoethoxyphosphinyl group, which aid in the stepwise assembly of DNA and RNA strands during solid-phase synthesis. Its structure allows for efficient coupling and deprotection cycles, making it essential in creating custom oligonucleotides for research in genomics, molecular diagnostics, and therapeutic applications, particularly in the development of antisense therapies and gene editing technologies.


Catalog Number M114796
CAS Number 134031-86-0
Molecular Formula C40H49N4O9P
Purity ≥95%
Storage -20°C
IUPAC Name 3-[[(2R,3S,5R)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-[di(propan-2-yl)amino]phosphoryl]oxypropanenitrile
InChI InChI=1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(47,50-23-11-22-41)51-26-36-35(24-37(52-36)43-25-29(5)38(45)42-39(43)46)53-40(30-12-9-8-10-13-30,31-14-18-33(48-6)19-15-31)32-16-20-34(49-7)21-17-32/h8-10,12-21,25,27-28,35-37H,11,23-24,26H2,1-7H3,(H,42,45,46)/t35-,36+,37+,54?/m0/s1
InChIKey BEMDXQXSHVUENL-JYQXRUAGSA-N
SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(N(C(C)C)C(C)C)OCCC#N)OC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

Request a Quote