5/'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2/'-DEOXYURIDINE

• CAT Number: M113096
• CAS Number: 134218-81-8
• Molecular Formula: C15H25IN2O5Si
• Molecular Weight: 468.36
• Purity: ≥95%
• Storage: Desiccate at +4C
• IUPAC Name: 1-[(2R,4S,5R)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-hydroxyoxolan-2-yl]-5-iodopyrimidine-2,4-dione
• InChI: InChI=1S/C15H25IN2O5Si/c1-15(2,3)24(4,5)22-8-11-10(19)6-12(23-11)18-7-9(16)13(20)17-14(18)21/h7,10-12,19H,6,8H2,1-5H3,(H,17,20,21)/t10-,11+,12+/m0/s1
• InChIKey: OOAVDWDELLQGHO-QJPTWQEYSA-N
• SMILES: CC(C)(C)[Si](C)(C)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)I)O

5′-O-(tert-butyldimethylsilyl)-5-iodo-2′-deoxyuridine(Cat No.:M113096) is a chemical compound used in organic synthesis and nucleoside chemistry. Its mode of action involves the introduction of a tert-butyldimethylsilyl (TBS) protecting group at the 5′-position of the uridine nucleoside. This protecting group prevents undesired reactions during subsequent chemical transformations, allowing for controlled modifications of the nucleoside. This compound is of great importance in the synthesis of nucleoside analogs and nucleotide derivatives, which have applications in antiviral and anticancer drug development.