5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

For research use only. Not for therapeutic Use.

  • CAT Number: I042309
  • CAS Number: 1197033-19-4
  • Molecular Formula: C49H54N7O8P
  • Molecular Weight: 899.97
  • Purity: ≥95%
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5′-ODMT cEt N-Bz A Phosphoramidite (Amidite)(Cat No.:I042309)is a chemical compound used in nucleic acid synthesis, particularly in the synthesis of oligonucleotides. It is a modified phosphoramidite derivative, where “5′-ODMT” refers to the 5′ position of the nucleotide being protected by an O-DMT (dimethoxytrityl) group, “cEt” represents a protected cytosine nucleoside with an ethyl group, “N-Bz” indicates a benzoyl protection on the amine group, and “A” refers to adenine. This compound enables efficient and selective incorporation of nucleotides during automated DNA/RNA synthesis, crucial for research and therapeutic applications.


Catalog Number I042309
CAS Number 1197033-19-4
Synonyms

N-[9-[(1S,3R,4R,6S,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-3-yl]purin-6-yl]benzamide

Molecular Formula C49H54N7O8P
Purity ≥95%
IUPAC Name N-[9-[(1S,3R,4R,6S,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-3-yl]purin-6-yl]benzamide
InChI InChI=1S/C49H54N7O8P/c1-32(2)56(33(3)4)65(61-28-14-27-50)64-43-42-47(55-31-53-41-44(51-30-52-45(41)55)54-46(57)35-15-10-8-11-16-35)63-48(43,34(5)62-42)29-60-49(36-17-12-9-13-18-36,37-19-23-39(58-6)24-20-37)38-21-25-40(59-7)26-22-38/h8-13,15-26,30-34,42-43,47H,14,28-29H2,1-7H3,(H,51,52,54,57)/t34-,42+,43-,47+,48-,65?/m0/s1
InChIKey XHEVZGBLRSIPCO-DZGFXGBPSA-N
SMILES C[C@H]1[C@]2([C@H]([C@@H](O1)[C@@H](O2)N3C=NC4=C(N=CN=C43)NC(=O)C5=CC=CC=C5)OP(N(C(C)C)C(C)C)OCCC#N)COC(C6=CC=CC=C6)(C7=CC=C(C=C7)OC)C8=CC=C(C=C8)OC

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