For research use only. Not for therapeutic Use.
5′-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog. 5′-ODMT cEt N-Bzm5 C Phosphoramidite Amidite blongs to modified antisense oligonucleotide[1].
| Catalog Number | I042307 |
| CAS Number | 1197033-17-2 |
| Synonyms | N-[1-[(1S,3R,4R,6S,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide |
| Molecular Formula | C49H56N5O9P |
| Purity | ≥95% |
| InChI | InChI=1S/C49H56N5O9P/c1-32(2)54(33(3)4)64(60-29-15-28-50)63-43-42-46(53-30-34(5)44(52-47(53)56)51-45(55)36-16-11-9-12-17-36)62-48(43,35(6)61-42)31-59-49(37-18-13-10-14-19-37,38-20-24-40(57-7)25-21-38)39-22-26-41(58-8)27-23-39/h9-14,16-27,30,32-33,35,42-43,46H,15,29,31H2,1-8H3,(H,51,52,55,56)/t35-,42+,43-,46+,48-,64?/m0/s1 |
| InChIKey | BDTXILPCBUAYPJ-USFFSJIASA-N |
| SMILES | CC1C2(C(C(O1)C(O2)N3C=C(C(=NC3=O)NC(=O)C4=CC=CC=C4)C)OP(N(C(C)C)C(C)C)OCCC#N)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC |
| Reference | [1]. Yu J, et al. Synthesis and antisense properties of 2′-O-(2S-methoxypropyl)-RNA-modified gapmer antisense oligonucleotides. ChemMedChem. 2014 Sep;9(9):2040-4. |
