5(S)-HpETE Lipid Maps® MS Standard

• CAT Number: R015959
• CAS Number: 71774-08-8
• Molecular Formula: C20H32O4
• Molecular Weight: 336.472
• Purity: ≥95%
• Synonyms: 5S-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
• Storage: -80°C
• IUPAC Name: (5S,6E,8Z,11Z,14Z)-5-hydroperoxyicosa-6,8,11,14-tetraenoic acid
• InChI: InChI=1S/C20H32O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(24-23)17-15-18-20(21)22/h6-7,9-10,12-14,16,19,23H,2-5,8,11,15,17-18H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-14+/t19-/m1/s1
• InChIKey: JNUUNUQHXIOFDA-JGKLHWIESA-N
• SMILES: CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)OO

5(S)-<wbr></wbr>HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-<wbr></wbr>LO on arachidonic acid. It is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs. 5(S)-<wbr></wbr>HpETE (1 µM) mediates the induction of the proto-<wbr></wbr>oncogene c-fos in TNF-<wbr></wbr>stimulated TA1 cells.