For research use only. Not for therapeutic Use.
5(Z),11(Z),14(Z)-<wbr></wbr>Eicosatrienoic acid is a polyunsaturated fatty acid found in various natural sources including maritime pine (<em>Pinus pinaster</em>) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods. A diet containing MPSO lowered high-<wbr></wbr>density lipoprotein and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to diminish cholesterol efflux <em>in vitro</em>. 5(Z),11(Z),14(Z)-<wbr></wbr>Eicosatrienoic acid methyl ester, when topically applied, reduces inflammatory processes, potentially by displacing arachidonic acid from phospholipid pools and reducing downstream inflammatory products such as prostaglandin E<sub>2</sub> and leukotrienes.
| Catalog Number | R030650 |
| CAS Number | 7019-85-4 |
| Synonyms | 5,11,14,20:3;Sciadonic Acid |
| Molecular Formula | C20H34O2 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | (5Z,11Z,14Z)-icosa-5,11,14-trienoic acid |
| InChI | InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,15-16H,2-5,8,11-14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,16-15- |
| InChIKey | PRHHYVQTPBEDFE-URZBRJKDSA-N |
| SMILES | CCCCCC=CCC=CCCCCC=CCCCC(=O)O |
| Reference | 1.Asset, G.,Leroy, A.,Bauge, E., et al. Effects of dietary maritime pine (Pinus pinaster)-seed oil on high-density lipoprotein levels and in vitro cholesterol efflux in mice expressing human apolipoprotein A-I. British Journal of Nutrition 84, 353-360 (20 |
