(5)6-Carboxytetramethylrhodamine

• CAT Number: I040867
• CAS Number: 117557-83-2
• Molecular Formula: C50H46N4O10+2
• Molecular Weight: 862.91
• Purity: ≥95%
• Synonyms: [9-(2,4-dicarboxyphenyl)-6-(dimethylamino)xanthen-3-ylidene]-dimethylazanium;[9-(2,5-dicarboxyphenyl)-6-(dimethylamino)xanthen-3-ylidene]-dimethylazanium
• InChI: InChI=1S/2C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31;1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)17-8-5-14(24(28)29)11-20(17)25(30)31/h2*5-13H,1-4H3,(H-,28,29,30,31)/p+2
• InChIKey: PYOXZPUMKLJOGA-UHFFFAOYSA-P
• SMILES: CN(C)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](C)C)C=C3O2)C4=C(C=C(C=C4)C(=O)O)C(=O)O.CN(C)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](C)C)C=C3O2)C4=C(C=CC(=C4)C(=O)O)C(=O)O

6-Carboxytetramethylrhodamine (TAMRA)(CAT: I040867) is a fluorescent dye widely used in biochemical and molecular biology applications, including fluorescence microscopy, flow cytometry, and quantitative PCR. It is particularly useful for labeling biomolecules such as peptides, proteins, and nucleic acids due to its strong fluorescence properties and high sensitivity. TAMRA’s carboxyl group allows for easy conjugation to other molecules, making it an essential tool in cellular imaging, protein-protein interaction studies, and drug screening assays. This dye is often employed in research involving materials chemistry and fluorescence-based biosensors for both scientific investigations and diagnostic applications.