For research use only. Not for therapeutic Use.
5,6,7-Trimethoxyflavone is a novel p38-α MAPK inhibitor with an anti-inflammatory effect. 5,6,7-Trimethoxyflavone is isolated from several plants including Zeyhera tuberculosa, Callicarpa japonica, and Kickxia lanigera[1].
| Catalog Number | I018287 |
| CAS Number | 973-67-1 |
| Synonyms | 5,6,7-trimethoxy-2-phenylchromen-4-one |
| Molecular Formula | C18H16O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H16O5/c1-20-15-10-14-16(18(22-3)17(15)21-2)12(19)9-13(23-14)11-7-5-4-6-8-11/h4-10H,1-3H3 |
| InChIKey | HJNJAUYFFFOFBW-UHFFFAOYSA-N |
| SMILES | COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)OC)OC |
| Reference | [1]. Hassan AHE, et al. Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators. Eur J Med Chem. 2019 Jul 9;180:253-267. |
