5HPP-33

• CAT Number: I014011
• CAS Number: 105624-86-0
• Molecular Formula: C20H21NO3
• Molecular Weight: 323.39
• Purity: ≥95%
• Synonyms: 5HPP-33; 5HPP 33; 5HPP33;;2-[2,6-Di(propan-2-yl)phenyl]-5-hydroxyisoindole-1,3-dione
• Solubility: Soluble in DMSO
• IUPAC Name: 2-[2,6-di(propan-2-yl)phenyl]-5-hydroxyisoindole-1,3-dione
• InChI: InChI=1S/C20H21NO3/c1-11(2)14-6-5-7-15(12(3)4)18(14)21-19(23)16-9-8-13(22)10-17(16)20(21)24/h5-12,22H,1-4H3
• InChIKey: LAKWINYVWJPHQW-UHFFFAOYSA-N
• SMILES: CC(C)C1=C(C(=CC=C1)C(C)C)N2C(=O)C3=C(C2=O)C=C(C=C3)O

5HPP-33（Cat No.:I014011）is a small molecule inhibitor of the GTPase enzyme RhoA, which plays a crucial role in regulating cell signaling, cytoskeletal dynamics, and cellular processes like migration, proliferation, and apoptosis. By targeting RhoA, 5HPP-33 can potentially modulate these cellular processes, making it a candidate for therapeutic use in cancer, fibrotic diseases, and other conditions where abnormal cell behavior is involved. Preclinical studies have shown its potential to inhibit tumor cell invasion and metastasis. However, further research and clinical trials are needed to assess its safety, efficacy, and potential applications in disease treatment.

Reference

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