(5Z,2E)-CU-3

• CAT Number: I018150
• CAS Number: 1815598-71-0
• Molecular Formula: C₁₆H₁₂N₂O₄S₃
• Molecular Weight: 392.47
• Purity: ≥95%
• Target: Metabolic Enzyme/Protease
• IUPAC Name: N-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzenesulfonamide
• InChI: 1S/C16H12N2O4S3/c19-15-14(10-4-6-12-7-5-11-22-12)24-16(23)18(15)17-25(20,21)13-8-2-1-3-9-13/h1-11,17H/b6-4+,14-10-
• InChIKey: YIUMXULORVBWLL-SPGDJUBISA-N
• SMILES: C1=CC=C(C=C1)S(=O)(=O)NN2C(=O)/C(=C/C=C/C3=CC=CO3)/SC2=S

(5Z,2E)-CU-3 (Cat No.: I018150) is an experimental small molecule compound with distinct stereochemical configurations. Preliminary findings suggest it targets key cellular mechanisms involved in inflammatory or oncogenic pathways. Through selective modulation of signaling proteins, it may suppress aberrant cell growth and immune dysregulation. Though still in early research phases, (5Z,2E)-CU-3 is being examined for its pharmacological potential in preclinical models. Further investigation of its safety, bioavailability, and therapeutic efficacy could pave the way for novel treatment options and clinical translation in the future.

Reference

[1]. Liu K, et al. A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response. J Lipid Res. 2016 Mar;57(3):368-79.