6-Alkynyl fucose

• CAT Number: I043936
• CAS Number: 935658-91-6
• Molecular Formula: C15H18O9
• Molecular Weight: 342.30
• Purity: ≥95%
• Synonyms: [(2S,3R,4R,5S)-4,5,6-triacetyloxy-2-ethynyloxan-3-yl] acetate
• InChI: InChI=1S/C15H18O9/c1-6-11-12(20-7(2)16)13(21-8(3)17)14(22-9(4)18)15(24-11)23-10(5)19/h1,11-15H,2-5H3/t11-,12+,13+,14-,15?/m0/s1
• InChIKey: FVDSJNFPNWVBGX-LUNVINKVSA-N
• SMILES: CC(=O)OC1C(OC(C(C1OC(=O)C)OC(=O)C)OC(=O)C)C#C

6-Alkynyl fucose is a tool in the study of protein?O-fucosylation[1]. 6-Alkynyl fucose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Reference

[1]. Esam Al-Shareffi, et al.6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin type-1 repeats by protein O-fucosyltransferases 1 and 2. Glycobiology. 2013 Feb;23(2):188-98.
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