6-Aminonicotinamide

• CAT Number: I011570
• CAS Number: 329-89-5
• Molecular Formula: C6H7N3O
• Molecular Weight: 137.14
• Purity: ≥95%
• Synonyms: 6-amino-3-pyridinecarboxamide
• Target: Dehydrogenase
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: 6-aminopyridine-3-carboxamide
• InChI: InChI=1S/C6H7N3O/c7-5-2-1-4(3-9-5)6(8)10/h1-3H,(H2,7,9)(H2,8,10)
• InChIKey: ZLWYEPMDOUQDBW-UHFFFAOYSA-N
• SMILES: C1=CC(=NC=C1C(=O)N)N

6-Aminonicotinamide（Cat No.:I011570）is an analog of niacinamide, widely used in biochemical research as an inhibitor of the pentose phosphate pathway (PPP). By targeting glucose-6-phosphate dehydrogenase, it disrupts NADPH production and cellular redox balance, inducing oxidative stress in cells. This mechanism makes 6-Aminonicotinamide valuable in cancer studies, as cancer cells rely heavily on PPP for growth and survival. It also serves as a tool to investigate cellular responses to oxidative stress and DNA damage, contributing to insights into metabolic pathways and potential therapeutic approaches for targeting cancer metabolism.