6-Chloropurine-9-β-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside

• CAT Number: M136880
• CAS Number: 135473-15-3
• Molecular Formula: C24H18ClFN4O5
• Molecular Weight: 496.879
• Purity: ≥95%
• Target: Nucleoside Antimetabolite/Analog
• Storage: -20°C
• IUPAC Name: [(2R,3R,4S,5R)-3-benzoyloxy-5-(6-chloropurin-9-yl)-4-fluorooxolan-2-yl]methyl benzoate
• InChI: InChI=1S/C24H18ClFN4O5/c25-20-18-21(28-12-27-20)30(13-29-18)22-17(26)19(35-24(32)15-9-5-2-6-10-15)16(34-22)11-33-23(31)14-7-3-1-4-8-14/h1-10,12-13,16-17,19,22H,11H2/t16-,17+,19-,22-/m1/s1
• InChIKey: UUXIUBHNOYWBNO-ZRAXVTTISA-N
• SMILES: C1=CC=C(C=C1)C(=O)OCC2C(C(C(O2)N3C=NC4=C3N=CN=C4Cl)F)OC(=O)C5=CC=CC=C5

6-Chloropurine-9-β-D-(3′,5′-di-O-benzoyl-2′-deoxy-2′-fluoro)arabinoriboside is a nucleoside analog used in pharmaceutical research, particularly in antiviral and anticancer drug development. Its structure includes a modified purine base (6-chloropurine) attached to a fluorinated arabinoriboside sugar moiety with benzoyl protection groups, making it an important intermediate for synthesizing nucleoside-based therapeutics. This compound’s unique chemical modifications enhance its stability and bioactivity, supporting the design of drugs targeting viral infections and cancer, contributing to advancements in medicinal chemistry.