6-Desacetyl-6-Bromo Palbociclib

For research use only. Not for therapeutic Use.

  • CAT Number: C000623
  • CAS Number: 851067-56-6
  • Molecular Formula: C₂₂H₂₆BrN₇O
  • Molecular Weight: 484.39
  • Purity: ≥95%
Inquiry Now

6-Desacetyl-6-Bromo Palbociclib(CAT: C000623) is an impurity of Palbociclib,(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Also, it is derived from 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one, which is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivative as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.


Catalog Number C000623
CAS Number 851067-56-6
Synonyms

6-Bromo-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Impurity F

Molecular Formula C₂₂H₂₆BrN₇O
Purity ≥95%
Solubility Aqueous Acid (Slightly), DMSO (Slightly, Heated), DMF (Slightly, Heated)
Appearance Off-White to Yellow Solid
Storage -20°C, Inert atmosphere
Reference

Finn, R., et al.: Breast Cancer Res., 11, 5 (2009); Li, X., et al.: PCT Int. Appl., WO 2014183520 A1 20141120 (2014);

Request a Quote