6-epi-Medroxy Progesterone-d3 17-Acetate

• CAT Number: R050512
• CAS Number: NA
• Molecular Formula: C₂₄H₃₁D₃O₄
• Molecular Weight: 389.54
• Purity: ≥95%
• Synonyms: (6β)-17-(Acetyloxy)-6-(methyl-d3)pregn-4-ene-3,20-dione; 17-Hydroxy-6β-(methyl-d3?)pregn-4-ene-3,20-dione Acetate; 17-Hydroxy-6β-(methyl-d3)progesterone Acetate; 6β-(Methyl-d3)-17α-hydroxyprogesterone Acetate; NSC 119085-d3
• Storage: -20°C
• IUPAC Name: [(6R,8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-6-(trideuteriomethyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
• InChI: InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18-,19+,20+,22-,23+,24+/m1/s1/i1D3
• InChIKey: PSGAAPLEWMOORI-VXCGPOLRSA-N
• SMILES: [2H]C([2H])([2H])[C@@H]1C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)OC(=O)C)C)[C@@]4(C1=CC(=O)CC4)

6-epi-Medroxy Progesterone-d3 17-Acetate is a deuterium-labeled analogue of Medroxyprogesterone acetate, a synthetic progestin used in hormone therapy and contraceptives. This compound targets progesterone receptors, modulating reproductive and menstrual functions. The deuterium labeling is beneficial for pharmacokinetic and metabolic studies, enabling precise tracking and quantification in biological systems using mass spectrometry. It is crucial in pharmaceutical research for understanding drug metabolism, optimizing therapeutic regimens, and developing new hormone-based treatments for conditions such as endometriosis, menstrual disorders, and certain cancers.