6-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

• CAT Number: L024931
• CAS Number: 1207623-96-8
• Molecular Formula: C14H17BFNO2
• Molecular Weight: 261.11
• Purity: ≥95%
• IUPAC Name: 6-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
• InChI: InChI=1S/C14H17BFNO2/c1-13(2)14(3,4)19-15(18-13)10-7-9-5-6-17-12(9)8-11(10)16/h5-8,17H,1-4H3
• InChIKey: AMTWQPUJRSKZAR-UHFFFAOYSA-N

6-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole(CAT: L024931) is a boron-containing indole derivative commonly used in synthetic and medicinal chemistry. The structure features a fluoro group at the 6-position of the indole ring and a boronic ester (dioxaborolane) at the 5-position. The boronic ester allows this compound to participate in Suzuki-Miyaura cross-coupling reactions, making it a versatile building block for constructing complex molecular architectures, particularly in the development of pharmaceuticals, agrochemicals, and functional materials. The presence of the fluoro group can enhance the compound’s metabolic stability and binding affinity in biological systems, which is valuable in drug discovery. This combination of functional groups makes it a useful intermediate for synthesizing diverse indole-based derivatives with potential biological activities.