For research use only. Not for therapeutic Use.
6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes[1].
| Catalog Number | R065606 |
| CAS Number | 7730-20-3 |
| Synonyms | 2-amino-3-(6-fluoro-1H-indol-3-yl)propanoic acid |
| Molecular Formula | C11H11FN2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C11H11FN2O2/c12-7-1-2-8-6(3-9(13)11(15)16)5-14-10(8)4-7/h1-2,4-5,9,14H,3,13H2,(H,15,16) |
| InChIKey | YMEXGEAJNZRQEH-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=C1F)NC=C2CC(C(=O)O)N |
| Reference | [1]. Miwa S, et al. Determination of serotonin turnover in the rat brain using 6-fluorotryptophan. J Neurochem. 1987 May;48(5):1577-80. [2]. D Sugden, et al. Changes in the rat sleep-wake cycle produced by DL-6-fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase. Psychopharmacology (Berl). 1981;74(4):369-73. |
