6-Hydroxy Warfarin-d5

• CAT Number: R046851
• CAS Number: 94820-64-1
• Molecular Formula: C19H16O5
• Molecular Weight: 329.363
• Purity: ≥95%
• Synonyms: 4,6-Dihydroxy-3-[3-oxo-1-(phenyl-d5)butyl]-2H-1-benzopyran-2-one; 3-(α-Acetonylbenzyl)-4,6-dihydroxycoumarin-d5
• Storage: -20°C
• IUPAC Name: 4,6-dihydroxy-3-[3-oxo-1-(2,3,4,5,6-pentadeuteriophenyl)butyl]chromen-2-one
• InChI: InChI=1S/C19H16O5/c1-11(20)9-14(12-5-3-2-4-6-12)17-18(22)15-10-13(21)7-8-16(15)24-19(17)23/h2-8,10,14,21-22H,9H2,1H3/i2D,3D,4D,5D,6D
• InChIKey: IQWPEJBUOJQPDE-VIQYUKPQSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1[2H])[2H])C(CC(=O)C)C2=C(C3=C(C=CC(=C3)O)OC2=O)O)[2H])[2H]

6-Hydroxy Warfarin-d5 is a deuterated analog of 6-hydroxy warfarin, where five hydrogen atoms have been replaced with deuterium. This isotopically labeled compound is used in pharmaceutical and biochemical research, particularly in studies focused on the metabolism, pharmacokinetics, and pharmacodynamics of warfarin, a widely used anticoagulant. The hydroxylation at the 6-position and deuterium labeling allow for precise tracking in analytical techniques like mass spectrometry, offering enhanced accuracy in monitoring the metabolic pathways and interactions of warfarin and its metabolites. 6-Hydroxy Warfarin-d5 is essential for researchers investigating warfarin metabolism, drug interactions, and the genetic factors influencing individual responses to warfarin therapy, providing critical data for optimizing anticoagulant treatment and reducing the risk of adverse effects.