For research use only. Not for therapeutic Use.
6-hydroxy Warfarin is a metabolite of (+)-warfarin (Item No. <span class=/itemid/>13526</span>), which is a weaker vitamin K antagonist than (-)-warfarin (Item No. <span class=/itemid/>13531</span>). Both isomers of warfarin are metabolized by the cytochrome P450 isoform 2C9 (CYP2C9); however, stereoselective metabolism also occurs, with CYP1A1 and CYP1A2 primarily responsible for metabolism of (+)-warfarin to 6-hydroxy warfarin.
| Catalog Number | R005455 |
| CAS Number | 17834-02-5 |
| Synonyms | 4,6-Dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one; 3-(α-Acetonylbenzyl)-4,6-dihydroxycoumarin; |
| Molecular Formula | C19H16O5 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 4,6-dihydroxy-3-(3-oxo-1-phenylbutyl)chromen-2-one |
| InChI | InChI=1S/C19H16O5/c1-11(20)9-14(12-5-3-2-4-6-12)17-18(22)15-10-13(21)7-8-16(15)24-19(17)23/h2-8,10,14,21-22H,9H2,1H3 |
| InChIKey | IQWPEJBUOJQPDE-UHFFFAOYSA-N |
| SMILES | CC(=O)CC(C1=CC=CC=C1)C2=C(C3=C(C=CC(=C3)O)OC2=O)O |
