For research use only. Not for therapeutic Use.
6-Ketocholestanol（Cat No.:R000772）is a cholesterol-derived oxysterol with applications in biochemical research, lipid metabolism studies, and steroid chemistry. The ketone functional group at the 6-position alters its biological activity, making it valuable for investigating cholesterol oxidation, membrane dynamics, and enzymatic pathways. It plays a crucial role in sterol regulatory mechanisms, neurosteroid research, and cholesterol transport studies. This compound is particularly useful in drug discovery, atherosclerosis research, and neurodegenerative disease studies, where oxysterols contribute to cell signaling, lipid homeostasis, and steroid hormone biosynthesis in physiological and pathological processes.
| CAS Number | 1175-06-0 |
| Synonyms | (3S,5S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,5,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-6-one |
| Molecular Formula | C27H46O2 |
| Purity | ≥95% |
| IUPAC Name | (3S,5S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,5,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-6-one |
| InChI | InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-16-25(29)24-15-19(28)11-13-27(24,5)23(20)12-14-26(21,22)4/h17-24,28H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,26-,27-/m1/s1 |
| InChIKey | JQMQKOQOLPGBBE-ZNCJEFCDSA-N |
| SMILES | C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=O)[C@@H]4[C@@]3(CC[C@@H](C4)O)C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
