6-Maleimidocaproic Acid Hydrazide, Trifluoroacetic Acid Salt

• CAT Number: R000676
• CAS Number: 151038-94-7
• Molecular Formula: C12H16F3N3O5
• Molecular Weight: 339.271
• Purity: ≥95%
• Synonyms: 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic Acid Hydrazide 2,2,2-Trifluoroacetate;?EMCH-TFA
• Storage: Store at RT
• IUPAC Name: 6-(2,5-dioxopyrrol-1-yl)hexanehydrazide;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C10H15N3O3.C2HF3O2/c11-12-8(14)4-2-1-3-7-13-9(15)5-6-10(13)16;3-2(4,5)1(6)7/h5-6H,1-4,7,11H2,(H,12,14);(H,6,7)
• InChIKey: DRURMGRBAVYWCL-UHFFFAOYSA-N
• SMILES: C1=CC(=O)N(C1=O)CCCCCC(=O)NN.C(=O)(C(F)(F)F)O

6-Maleimidocaproic Acid Hydrazide, Trifluoroacetic Acid Salt is a bioconjugation reagent used in peptide and protein chemistry. This compound features a maleimide group that facilitates selective coupling with thiol-containing biomolecules, enabling the formation of stable thioether bonds. The trifluoroacetic acid salt form enhances solubility and stability in aqueous solutions. Applications include targeted drug delivery, antibody-drug conjugates, and labeling studies in proteomics. Its utility in site-specific modifications makes it valuable in developing therapeutic and diagnostic bioconjugates.