For research use only. Not for therapeutic Use.
6-Maleimidocaproic acid sulfo-NHS sodium(Cat No.:R000672)is a chemical reagent commonly used in bioconjugation and protein labeling. It consists of a maleimide group that reacts with thiol groups on proteins or peptides, enabling the covalent attachment of various biomolecules for research or therapeutic applications. The sulfo-NHS ester group facilitates the reaction in aqueous conditions, enhancing its stability and reducing nonspecific binding. This reagent is frequently employed in the preparation of antibody-drug conjugates (ADCs), biosensors, and other bioactive molecules, enabling precise targeting and efficient delivery in drug development and diagnostic research.
CAS Number | 215312-86-0 |
Synonyms | sodium;1-[6-(2,5-dioxopyrrol-1-yl)hexanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate |
Molecular Formula | C14H15N2NaO9S |
Purity | ≥95% |
IUPAC Name | sodium;1-[6-(2,5-dioxopyrrol-1-yl)hexanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate |
InChI | InChI=1S/C14H16N2O9S.Na/c17-10-5-6-11(18)15(10)7-3-1-2-4-13(20)25-16-12(19)8-9(14(16)21)26(22,23)24;/h5-6,9H,1-4,7-8H2,(H,22,23,24);/q;+1/p-1 |
InChIKey | MIDXXTLMKGZDPV-UHFFFAOYSA-M |
SMILES | C1C(C(=O)N(C1=O)OC(=O)CCCCCN2C(=O)C=CC2=O)S(=O)(=O)[O-].[Na+] |