6-Maleimidohexanoic acid N-hydroxysuccinimide ester

• CAT Number: I004078
• CAS Number: 55750-63-5
• Molecular Formula: C14H16N2O6
• Molecular Weight: 308.29
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate
• InChI: InChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
• InChIKey: VLARLSIGSPVYHX-UHFFFAOYSA-N
• SMILES: C1CC(=O)N(C1=O)OC(=O)CCCCCN2C(=O)C=CC2=O

6-Maleimidohexanoic acid N-hydroxysuccinimide ester (Cat No.:I004078) is a heterobifunctional crosslinker widely used in bioconjugation chemistry. It contains a maleimide group and a N-hydroxysuccinimide (NHS) ester group, allowing for specific and efficient coupling of thiol- and amine-containing molecules, respectively. EMCS is particularly valuable in the preparation of hapten conjugates and enzyme immunoconjugates, where it enables site-specific and stable attachment of small molecules or enzymes to antibodies or other proteins of interest.