6-Mercaptopurine (6-MP) Monohydrate

• CAT Number: A000105
• CAS Number: 6112-76-1
• Molecular Formula: C5H6N4OS
• Molecular Weight: 170.19
• Purity: ≥95%
• Target: Nucleoside Antimetabolite/Analog
• Storage: Store at -20°C
• IUPAC Name: 3,7-dihydropurine-6-thione;hydrate
• InChI: InChI=1S/C5H4N4S.H2O/c10-5-3-4(7-1-6-3)8-2-9-5;/h1-2H,(H2,6,7,8,9,10);1H2
• InChIKey: WFFQYWAAEWLHJC-UHFFFAOYSA-N
• SMILES: C1=NC2=C(N1)C(=S)N=CN2.O

6-Mercaptopurine (6-MP) Monohydrate（Cat No.:A000105）is a purine analog widely used in the treatment of acute lymphoblastic leukemia (ALL) and other hematological malignancies. It interferes with DNA and RNA synthesis by incorporating into nucleic acids and inhibiting purine metabolism, leading to impaired cell division and apoptosis in rapidly proliferating cells. 6-MP is also used as an immunosuppressant for conditions like inflammatory bowel disease. The monohydrate form ensures enhanced stability and solubility. It remains a critical compound in oncology and immunology research, contributing to the understanding of antimetabolite therapies.