6-MPR

• CAT Number: M053742
• CAS Number: 14675-48-0
• Molecular Formula: C11H14N4O4
• Molecular Weight: 266.25
• Purity: ≥95%
• Synonyms: (2R,3R,5R)-2-(hydroxymethyl)-5-(6-methylpurin-9-yl)oxolane-3,4-diol
• IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-methylpurin-9-yl)oxolane-3,4-diol
• InChI: InChI=1S/C11H14N4O4/c1-5-7-10(13-3-12-5)15(4-14-7)11-9(18)8(17)6(2-16)19-11/h3-4,6,8-9,11,16-18H,2H2,1H3/t6-,8-,9-,11-/m1/s1
• InChIKey: FIGBCBGMUIGJBD-PNHWDRBUSA-N
• SMILES: CC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O

6-Mercaptopurine riboside (6-MPR) （Cat No.:M053742）is a purine analogue and a metabolite of the chemotherapy drug 6-mercaptopurine (6-MP). It is involved in the inhibition of purine synthesis, which disrupts DNA and RNA synthesis, leading to the suppression of cell growth and division. 6-MPR is primarily used in the treatment of certain cancers, such as leukemia, and autoimmune disorders like Crohn’s disease and ulcerative colitis. By interfering with the synthesis of purine nucleotides, it helps manage diseases involving overactive cell proliferation and immune system activity.