For research use only. Not for therapeutic Use.
DNQX is a competitive, non-<wbr></wbr>NMDA glutamate receptor antagonist (IC<sub>50</sub>s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively <em>versus</em> IC<sub>50</sub> = 40 μM for NMDA receptors). This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-<wbr></wbr>term potentiation in the hippocampus.
| Catalog Number | R000094 |
| CAS Number | 2379-57-9 |
| Synonyms | 6,7-Dinitro-2,3-dihydroxyquinoxaline; 6,7-Dinitroquinoxaline-2,3-(1H,4H)-dione; DNQX |
| Molecular Formula | C8H4N4O6 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Storage | -20°C |
| InChIKey | RWVIMCIPOAXUDG-UHFFFAOYSA-N |
