6,8-Dihydro-7H-pyrrolo[2,3-g]benzothiazol-7-one

• CAT Number: C000166
• CAS Number: 222036-27-3
• Molecular Formula: C₉H₆N₂OS
• Molecular Weight: 190.22
• Purity: ≥95%
• Synonyms: 6H-Thiazolo[5,4-e]indol-7(8H)-one
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• Appearance: Pale Beige Solid
• Storage: -20°C, Inert atmosphere

6,8-Dihydro-7H-pyrrolo[2,3-g]benzothiazol-7-one(CAT: C000166) is a crucial intermediate compound used in the synthesis of Imidazolo-oxindole PKR inhibitor C16. Its action method lies in serving as a key building block during the chemical synthesis of this specific inhibitor. In the pharmaceutical and organic chemistry domains, this intermediate plays a pivotal role in the production of targeted compounds designed to inhibit PKR (Protein Kinase R), which is involved in various cellular processes and can be a potential target for medical research and drug development.

Reference

Jammi, N., et al.: Biochem. Biophys. Res. Commun., 308, 50 (2003); Ingrand, S., et al.: Neurosci. Lett., 409, 192 (2006); Chen, H., et al.: Eur. J. Neurosci., 28, 2003 (2008); Couturier, J., et al.: J. Biol. Chem., 285, 1272 (2010)