For research use only. Not for therapeutic Use.
6877002 (Cat.No:I011251) is a CD40-TRAF6 interaction inhibitor. Suppresses CD40-induced IL-1β and IL-6 expression in macrophages in vitro. Improves insulin sensitivity, reduces adipose tissue inflammation, and ameliorates hepatosteatosis in diet-induced obese mice.
| Catalog Number | I011251 |
| CAS Number | 433249-94-6 |
| Synonyms | 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one |
| Molecular Formula | C17H17NO |
| Purity | ≥95% |
| Target | NF-κB |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage | Store at 4℃ |
| IUPAC Name | (E)-3-(2,5-dimethylanilino)-1-phenylprop-2-en-1-one |
| InChI | InChI=1S/C17H17NO/c1-13-8-9-14(2)16(12-13)18-11-10-17(19)15-6-4-3-5-7-15/h3-12,18H,1-2H3/b11-10+ |
| InChIKey | SARYOFMRLSHZFE-ZHACJKMWSA-N |
| SMILES | CC1=CC(=C(C=C1)C)NC=CC(=O)C2=CC=CC=C2 |
