7α-Thiomethyl Spironolactone

• CAT Number: R006829
• CAS Number: 38753-77-4
• Molecular Formula: C23H32O3S
• Molecular Weight: 388.566
• Purity: ≥95%
• Synonyms: 17α-Hydroxy-7α-(methylthio)-3-oxo-pregn-4-ene-21-carboxylic Acid γ-Lactone;?SC 26519; 7α-Thiomethylspirolactone; 7α-Thiomethyl-SL
• Storage: Store at RT
• IUPAC Name: (7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-7-methylsulfanylspiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,5/'-oxolane]-2/',3-dione
• InChI: InChI=1S/C23H32O3S/c1-21-8-4-15(24)12-14(21)13-18(27-3)20-16(21)5-9-22(2)17(20)6-10-23(22)11-7-19(25)26-23/h12,16-18,20H,4-11,13H2,1-3H3/t16-,17-,18+,20+,21-,22-,23+/m0/s1
• InChIKey: FWRDLPQBEOKIRE-RJKHXGPOSA-N
• SMILES: CC12CCC(=O)C=C1CC(C3C2CCC4(C3CCC45CCC(=O)O5)C)SC

7α-Thiomethyl Spironolactone is a key metabolite of the diuretic drug Spironolactone, crucial for advanced pharmaceutical and biochemical research. This compound is instrumental in studying the pharmacokinetics, metabolism, and therapeutic effects of Spironolactone. Its unique structure allows for detailed analysis of metabolic pathways and drug interactions. 7α-Thiomethyl Spironolactone is highly valued for its purity and stability, making it an indispensable tool in the development of effective treatments for conditions like hypertension and heart failure.