For research use only. Not for therapeutic Use.
7(8)-DiHDPA is a major metabolite of docosahexaenoic acid (DHA; Item No. <span class=/itemid/>90310</span>) that is produced <em>via</em> oxidation by cytochrome P450 epoxygenases. Epoxygenase metabolites of DHA, including 7(8)-DiHDPA, suppress aggregation and thromboxane synthesis in isolated platelets.
| Catalog Number | R046025 |
| CAS Number | 168111-93-1 |
| Synonyms | 7,8-dihydroxydocosa-4Z,10Z,13Z,16Z,19Z-pentaenoic acid |
| Molecular Formula | C22H34O4 |
| Purity | ≥95% |
| Target | Endogenous metabolite |
| Storage | -20°C |
| InChI | InChI=1S/C22H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-14-17-20(23)21(24)18-15-13-16-19-22(25)26/h3-4,6-7,9-10,12-15,20-21,23-24H,2,5,8,11,16-19H2,1H3,(H,25,26)/b4-3-,7-6-,10-9-,14-12-,15-13- |
| InChIKey | DPZIOENSPXELQY-MPQBXPHNSA-N |
| SMILES | CC/C=CC/C=CC/C=CC/C=CCC(O)C(O)C/C=CCCC(O)=O |
| Reference | 1.VanRollins, M.,Baker, R.C.,Sprecher, H., et al. Oxidation of docosahexaenoic acid by rat liver microsomes. J. Biol. Chem. 259(9), 5776-5783 (1984). |
