7-Aminobenzo[a]pyrene

• CAT Number: R004398
• CAS Number: 72297-05-3
• Molecular Formula: C20H13N
• Molecular Weight: 267.331
• Purity: ≥95%
• Storage: 2°C to 8°C
• IUPAC Name: benzo[a]pyren-7-amine
• InChI: InChI=1S/C20H13N/c21-18-6-2-5-15-16-10-9-13-4-1-3-12-7-8-14(11-17(15)18)20(16)19(12)13/h1-11H,21H2
• InChIKey: CYLGRLTVDYSTRG-UHFFFAOYSA-N
• SMILES: C1=CC2=C3C(=C1)C=CC4=C3C(=CC5=C4C=CC=C5N)C=C2

7-Aminobenzo[a]pyrene is a potent polycyclic aromatic hydrocarbon (PAH) and a known carcinogen, primarily formed through the incomplete combustion of organic materials. This compound features an amino group at the 7-position of the benzo[a]pyrene structure, which enhances its biological activity and potential for DNA interaction. Research indicates that 7-Aminobenzo[a]pyrene can form DNA adducts, leading to mutagenic changes that contribute to tumorigenesis. It serves as a model compound in toxicology studies investigating the mechanisms of PAH-induced carcinogenicity. Understanding its effects on cellular processes is crucial for assessing environmental health risks associated with exposure to PAHs in contaminated air, soil, and food.