7-Carboxy-7-deazaguanine

• CAT Number: L002727
• CAS Number: 92636-62-9
• Molecular Formula: C7H6N4O3
• Molecular Weight: 194.15
• Purity: ≥95%
• IUPAC Name: 2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidine-5-carboxylic acid
• InChI: InChI=1S/C7H6N4O3/c8-7-10-4-3(5(12)11-7)2(1-9-4)6(13)14/h1H,(H,13,14)(H4,8,9,10,11,12)
• InChIKey: XIUIRSLBMMTDSK-UHFFFAOYSA-N

7-Carboxy-7-deazaguanine(CAT: L002727) is a modified purine derivative that plays a critical role in biochemical research, particularly in studies related to nucleic acid metabolism and enzyme interactions. This compound, which lacks the nitrogen atom typically found in the purine ring, is involved in the biosynthesis of queuosine, a rare nucleoside modification found in transfer RNA (tRNA). Its carboxyl group provides unique chemical properties, making it valuable for probing enzyme mechanisms, studying molecular interactions, and synthesizing nucleic acid analogs. Due to its structural similarity to guanine, it can be used in research on genetic regulation and nucleic acid-based therapeutics.