7-Deaza-2'-C-ethynyladenosine

• CAT Number: M013579
• CAS Number: 1044589-82-3
• PubChem Substance ID: 44633776
• Molecular Formula: C13H14N4O4
• Molecular Weight: 290.28
• Purity: 98%
• Synonyms: 7-Deaza-2′-C-ethynyladenosine;(2R,3R,4R,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;7-Deaza-2′-C-acetylene-adenosine
• Target: Cell Cycle/DNA Damage
• Storage: Store at -20°C
• IUPAC Name: (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-(hydroxymethyl)oxolane-3,4-diol
• InChI: InChI=1S/C13H14N4O4/c1-2-13(20)9(19)8(5-18)21-12(13)17-4-3-7-10(14)15-6-16-11(7)17/h1,3-4,6,8-9,12,18-20H,5H2,(H2,14,15,16)/t8-,9-,12-,13-/m1/s1
• InChIKey: NKRAIOQPSBRMOV-OTMMVIPVSA-N
• SMILES: C#CC1(C(C(OC1N2C=CC3=C2N=CN=C3N)CO)O)O

NITD008（Cat No.:M013579）is a highly effective and selective inhibitor of flaviviruses, showing remarkable potency with an EC50 of 0.64 μM against Dengue Virus Type 2 (DENV-2). This compound demonstrates strong antiviral activity, specifically targeting the replication and spread of flaviviruses, including dengue virus. Its ability to inhibit viral proliferation at low concentrations highlights its potential as a promising therapeutic agent for flavivirus infections. NITD008’s specific mechanism of action provides a valuable tool for further research and drug development in the quest to combat flavivirus-related diseases.