7-Deaza-2'-dA

• CAT Number: L047466
• CAS Number: 60129-59-1
• Molecular Formula: C11H14N4O3
• Molecular Weight: 250.25
• Purity: ≥95%
• IUPAC Name: (2R,3S,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)oxolan-3-ol
• InChI: InChI=1S/C11H14N4O3/c12-10-6-1-2-15(11(6)14-5-13-10)9-3-7(17)8(4-16)18-9/h1-2,5,7-9,16-17H,3-4H2,(H2,12,13,14)/t7-,8+,9+/m0/s1
• InChIKey: NIJSNUNKSPLDTO-DJLDLDEBSA-N
• SMILES: C1[C@@H]([C@H](O[C@H]1N2C=CC3=C(N=CN=C32)N)CO)O

7-Deaza-2′-deoxyadenosine (7-Deaza-2′-dA)（Cat No.:L047466）is a modified nucleoside analogue commonly used in biochemical and molecular biology research. It replaces adenine in DNA with a deaza-adenine, altering the hydrogen bonding and base-pairing properties. This modification makes it useful in studying DNA replication, transcription, and protein-DNA interactions. 7-Deaza-2′-dA is often employed to investigate the effects of nucleotide modifications on enzyme activity and DNA structure. It is also used in the development of antiviral and anticancer agents due to its ability to disrupt normal nucleic acid functions in cells.