7-Desmethyl-agomelatine-d3

• CAT Number: S000477
• CAS Number: 2749427-92-5
• Molecular Formula: C14H12D3NO2
• Molecular Weight: 232.29
• Purity: ≥95%
• IUPAC Name: 2,2,2-trideuterio-N-[2-(7-hydroxynaphthalen-1-yl)ethyl]acetamide
• InChI: InChI=1S/C14H15NO2/c1-10(16)15-8-7-12-4-2-3-11-5-6-13(17)9-14(11)12/h2-6,9,17H,7-8H2,1H3,(H,15,16)/i1D3
• InChIKey: UNTZQBYXDYYXIY-FIBGUPNXSA-N
• SMILES: CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)O

7-Desmethyl-agomelatine-d3（Cat No.:S000477） is a deuterated form of 7-desmethyl-agomelatine, where three hydrogen atoms are replaced with deuterium. This deuterated variant is utilized to enhance the understanding of the drug’s metabolic processes and pharmacokinetics. 7-Desmethyl-agomelatine is a significant metabolite of agomelatine, an antidepressant that acts on melatonin receptors to regulate circadian rhythms and mood. By modifying the compound with deuterium, researchers can explore how it affects metabolic stability and the potential changes in the drug’s interaction with metabolic enzymes, aiding in the development of more effective and targeted therapies for depressive disorders.