For research use only. Not for therapeutic Use.
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2].
| Catalog Number | R002120 |
| CAS Number | 5725-91-7 |
| Synonyms | 7-ethoxyphenoxazin-3-one |
| Molecular Formula | C14H11NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C14H11NO3/c1-2-17-10-4-6-12-14(8-10)18-13-7-9(16)3-5-11(13)15-12/h3-8H,2H2,1H3 |
| InChIKey | CRCWUBLTFGOMDD-UHFFFAOYSA-N |
| SMILES | CCOC1=CC2=C(C=C1)N=C3C=CC(=O)C=C3O2 |
| Reference | [1]. C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62. [2]. Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90. |
