For research use only. Not for therapeutic Use.
7-Fluorotryptamine hydrochloride(CAT: M043285) is a fluorinated tryptamine derivative and a potent agonist of GPRC5A, an orphan G protein-coupled receptor involved in immune signaling and cancer research. It induces GPRC5A-mediated β-arrestin recruitment, modulating TNFα-induced gene expression, including IL41A, CXCL10, and CSF2. Exhibiting low cytotoxicity in mammalian cell lines up to 100 μM, it is widely used in biochemical and cellular studies. The hydrochloride salt ensures enhanced solubility and stability for pharmacological and mechanistic investigations. Ideal for drug discovery and receptor pathway analysis, it is for research use only; not for human or clinical applications.
| Catalog Number | M043285 |
| CAS Number | 159730-09-3 |
| Synonyms | 2-(7-fluoro-1H-indol-3-yl)ethanamine;hydrochloride |
| Molecular Formula | C10H12ClFN2 |
| Purity | ≥95% |
| IUPAC Name | 2-(7-fluoro-1H-indol-3-yl)ethanamine;hydrochloride |
| InChI | InChI=1S/C10H11FN2.ClH/c11-9-3-1-2-8-7(4-5-12)6-13-10(8)9;/h1-3,6,13H,4-5,12H2;1H |
| InChIKey | JWAZOMQARDNFMN-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C(=C1)F)NC=C2CCN.Cl |
