7-Hydroxy Granisetron-d3 Hydrochloride

• CAT Number: R048195
• CAS Number: NA
• Molecular Formula: C₁₈H₂₂D₃ClN₄O₂
• Molecular Weight: 367.89
• Purity: ≥95%
• Synonyms: 7-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide-d3 Hydrochloride
• Storage: Store at -20°C
• IUPAC Name: 7-hydroxy-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1-(trideuteriomethyl)indazole-3-carboxamide;hydrochloride
• InChI: InChI=1S/C18H24N4O2.ClH/c1-21-12-5-3-6-13(21)10-11(9-12)19-18(24)16-14-7-4-8-15(23)17(14)22(2)20-16;/h4,7-8,11-13,23H,3,5-6,9-10H2,1-2H3,(H,19,24);1H/t11?,12-,13+;/i2D3
• InChIKey: MBSNWMLKHVHIJB-DVWGCCALSA-N
• SMILES: CN1C2CCCC1CC(C2)NC(=O)C3=NN(C4=C3C=CC=C4O)C.Cl

7-Hydroxy Granisetron-d3 Hydrochloride（Cat No.:R048195） is a deuterated form of 7-hydroxy granisetron, featuring three deuterium atoms, which enhances its stability and facilitates precise detection in pharmacokinetic and metabolic studies. Granisetron is commonly used as an antiemetic to prevent nausea and vomiting associated with chemotherapy. The deuterated hydrochloride form improves solubility and handling, making it ideal for research applications. 7-Hydroxy Granisetron-d3 Hydrochloride is crucial for studying the metabolism of granisetron and optimizing its therapeutic use, thereby aiding in the development of more effective treatments for chemotherapy-induced side effects.