7-Hydroxy Memantine Hydrochloride

• CAT Number: R050216
• CAS Number: 356572-08-2
• Molecular Formula: C12H22ClNO
• Molecular Weight: 231.764
• Purity: ≥95%
• Synonyms: 3-Amino-5,7-dimethyltricyclo[3.3.1.13,7]decan-1-ol Hydrochloride; 1-Amino-3,5-dimethyl-7-hydroxyadamantane Hydrochloride; 1-Amino-7-hydroxy-3,5-dimethyladamantane
• Storage: Store at -20°C
• IUPAC Name: 3-amino-5,7-dimethyladamantan-1-ol;hydrochloride
• InChI: InChI=1S/C12H21NO.ClH/c1-9-3-10(2)5-11(13,4-9)8-12(14,6-9)7-10;/h14H,3-8,13H2,1-2H3;1H
• InChIKey: VSLXJPGBEIWMTR-UHFFFAOYSA-N
• SMILES: CC12CC3(CC(C1)(CC(C2)(C3)O)N)C.Cl

7-Hydroxy Memantine Hydrochloride is a hydroxylated derivative of memantine, an FDA-approved drug used in the treatment of Alzheimer’s disease. Memantine functions as an NMDA (N-methyl-D-aspartate) receptor antagonist, protecting neurons from excitotoxicity by regulating glutamate activity in the brain. The hydroxylation at the 7-position in 7-Hydroxy Memantine may affect its pharmacokinetics or biological activity, making it of interest for further research in neuroprotection and neurological disorders. This derivative is used in studies to explore potential improvements in the therapeutic efficacy and safety profile of memantine or to investigate novel treatments for neurodegenerative diseases.