7-Methyladenine

• CAT Number: I014013
• CAS Number: 935-69-3
• Molecular Formula: C6H7N5
• Molecular Weight: 149.16
• Purity: ≥95%
• Synonyms: 7-Methyladenine; NSC 7857; NSC-7857; NSC7857;7H-Purin-6-amine, 7-methyl- (9CI)
• Solubility: Soluble in DMSO
• IUPAC Name: 7-methylpurin-6-amine
• InChI: InChI=1S/C6H7N5/c1-11-3-10-6-4(11)5(7)8-2-9-6/h2-3H,1H3,(H2,7,8,9)
• InChIKey: HCGHYQLFMPXSDU-UHFFFAOYSA-N
• SMILES: CN1C=NC2=NC=NC(=C21)N

7-Methyladenine（Cat No.:I014013） is a naturally occurring base modification of adenine in DNA and RNA. It is formed through methylation reactions and can serve as a potential marker for monitoring exposure to methylating carcinogens. Methylation of adenine residues can lead to genetic mutations and contribute to the development of cancer. Therefore, the detection and quantification of 7-methyladenine levels in DNA or biological samples can provide insights into the extent of exposure to methylating carcinogens and aid in assessing associated risks or evaluating the efficacy of preventive measures.

Reference

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