7-Prenyloxyaromadendrin

• CAT Number: I044905
• CAS Number: 78876-50-3
• Molecular Formula: C20H20O6
• Molecular Weight: 356.37
• Purity: ≥95%
• Synonyms: (2R,3R)-3,5-dihydroxy-2-(4-hydroxyphenyl)-7-(3-methylbut-2-enoxy)-2,3-dihydrochromen-4-one
• InChI: InChI=1S/C20H20O6/c1-11(2)7-8-25-14-9-15(22)17-16(10-14)26-20(19(24)18(17)23)12-3-5-13(21)6-4-12/h3-7,9-10,19-22,24H,8H2,1-2H3/t19-,20+/m0/s1
• InChIKey: CITFYDYEWQIEPX-VQTJNVASSA-N
• SMILES: CC(=CCOC1=CC(=C2C(=C1)OC(C(C2=O)O)C3=CC=C(C=C3)O)O)C

7-Prenyloxyaromadendrin is a flavonoid from Pterocaulon alopecuroides with antitumor activity. 7-Prenyloxyaromadendrin shows good antiproliferative activity in tumor cell lines[1][2].
7-Prenyloxyaromadendrin (compound 5) shows antiproliferative activity with GI50 values in the range 16-20 μM in A549, HBL-100, HeLa, SW1573, T-47D cells[2].
7-Prenyloxyaromadendrin (compound 5) is inactive on B. subtilis and B. cereus (there is no zone of inhibition at the concentration of 50 μg/disk)[1].

Reference

[1]. Rosana Alarcón, et al. Flavonoids from Pterocaulon alopecuroides with antibacterial activity. Planta Med. 2008 Oct;74(12):1463-7.
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[2]. Quírico A Castillo, et al. Secondary Metabolites from Pterocaulon alopecuroides and their Antiproliferative Activities. Pharmacognosy Journal,2019,11,3,493-495.