77-LH-28-1 Oxalate

• CAT Number: I012869
• CAS Number: 560085-12-3
• Molecular Formula: C23H34N2O5
• Molecular Weight: 418.53
• Purity: ≥95%
• Synonyms: 1-[3-(4-Butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one Oxalate
• IUPAC Name: 1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one;oxalic acid
• InChI: InChI=1S/C21H32N2O.C2H2O4/c1-2-3-7-18-12-16-22(17-13-18)14-6-15-23-20-9-5-4-8-19(20)10-11-21(23)24;3-1(4)2(5)6/h4-5,8-9,18H,2-3,6-7,10-17H2,1H3;(H,3,4)(H,5,6)
• InChIKey: SWMAYCPSQGJJLL-UHFFFAOYSA-N
• SMILES: CCCCC1CCN(CC1)CCCN2C(=O)CCC3=CC=CC=C32.C(=O)(C(=O)O)O

77-LH-28-1 Oxalate(CAT: I012869) is a potent and selective agonist of the G protein-coupled receptor GPR40 (also known as FFAR1), a key receptor involved in glucose metabolism and insulin secretion. By activating GPR40, it enhances insulin release in a glucose-dependent manner, making it a valuable tool in diabetes and metabolic disease research. Its specificity for GPR40 allows for detailed exploration of this receptor’s role in β-cell function and glucose homeostasis. 77-LH-28-1 Oxalate is particularly useful for developing and studying novel therapeutic approaches for type 2 diabetes and related metabolic disorders.